Kingella kingae and Osteoarticular Infections

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Kingella kingae infections in children

BACKGROUND Improvements in culture techniques and molecular detection methods have led to findings indicating that, particularly in infants and young children, Kingella kingae is a significantly more important pathogen than previously thought. However, despite this, the pediatric community is still largely unaware of the existence of this organism. The aim of this review is therefore to summari...

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Detection of Kingella kingae osteoarticular infections in children by oropharyngeal swab PCR.

OBJECTIVE The purpose of this study was to investigate if oropharyngeal swab polymerase chain reaction (PCR) could predict osteoarticular infection (OAI) due to Kingella kingae in young children. METHODS One hundred twenty-three consecutive children aged 6 to 48 months presenting with atraumatic osteoarticular complaints were prospectively studied. All had a clinical evaluation, imaging, and ...

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The rtxA toxin gene of Kingella kingae: a pertinent target for molecular diagnosis of osteoarticular infections.

Kingella kingae is an emerging osteoarticular pathogen in young children. Its isolation by traditional culture methods remains difficult, underscoring the need to implement other diagnostic methods for its detection and identification, such as nucleic acid amplification tests. Although the genome of this bacterium has not yet been sequenced, a toxin named RTX has been identified. The goal of th...

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Small risk of osteoarticular infections in children with asymptomatic oropharyngeal carriage of Kingella kingae.

The aim of this study was to evaluate the absolute risk for children younger than 4 years of age with asymptomatic oropharyngeal carriage of Kingella kingae to sustain an osteoarticular infection. The rate of K. kingae carriage in the oropharyngeal mucosa was 9% among healthy children, and the risk for an asymptomatic carrier to develop an osteoarticular infection due to K. Kingae was estimated...

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Kingella kingae keratitis.

We present the first two cases of Kingella kingae keratitis in adults. This species is a rare isolate from ophthalmic samples for which final identification was obtained with matrix-assisted laser desorption ionization-time of flight mass spectrometry. One of the patients recovered uneventfully with topical therapy. Results from the second patient cannot be confirmed as he was lost to follow-up.

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ژورنال

عنوان ژورنال: Pediatrics

سال: 2019

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.2019-1509